Downtown LA – Rapidly renovating, it's a great place for a meal or to catch a show at the Walt Disney Concert Hall and best of all, it's reachable by Metro.
Universal City – Home to Universal Studios and a short trip via US Highway 101 or the Metro Red Line.
Studio City – Among other attractions, offers perhaps the highest density of sushi restaurants in Los Angeles.
West Hollywood – This may be Hollywood's less-famous sibling, but it boasts a bustling nightlife and features excellent restaurants, clubs, and hotels.
Beverly Hills – Home of 90210, and a few other zip codes.